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J. Peter Wells, an expose writer, arrives on an island off the coast of South America (no country is identified), to complete a book on voodoo, juju, Macumba, mojo and other cult beliefs, which he believes are responsible for a series of unsolved murders on the island. Wealthy landowner Venis de Vias warns him against stirring up the natives, especially any efforts to lessen the prestige of the reigning voodoo queen, Mama Rata-loi. The arrival of Wells' daughter, Sara, and her husband, Warren, on a honeymoon trip stirs the pot to boiling and the natives become restless. The most restless of all is Mama Rata-loi, who asserts her powers and puts a spell on Venis de Vias. The next thing Warren knows, he is both tightly bound hand and foot and about to become the one who is chosen to die in a voodoo ceremony.
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